Wikipedia says: The term picotechnology is a portmanteau of picometer and technology, intended to parallel the term nanotechnology. It is a hypothetical future level of technological manipulation of matter, on the scale of trillionths of a meter or picoscale (10-12). Pure non-sense we have sold picotechnology or atoms for 20 years. Not sold in the USA. You can treat, but you can not cure medical problems by using same old technology, methods and thinking! Next generation of medicine is Pico-Medicine! Picotechnology will be the biggest change in the world since electricity as its a 1000 times smaller than nanotechnology and we have done it for 20 years. Industries we have thousands products for our medical, agriculture, cleaning and chemical replacement. Please share and stop toxic based products!

Pico-Medicine Technology LLC Not sold in the USA.
805 Cottage Hill Way, Brandon, FL 33511 800 995-9203, 336 306-0193
Email donwilshe@biobased.us Emails go to spam, Best Call Us For Questions, Open 7 days EST 10AM to 10PM!


Bacteria's Fungi's Virus's Insects's Nursery Tours's
Picotechnology-Industries Pico-Medicine Picocides Pico-Technology Picosoap


For More About Pico-Technology,----- Pico skin Relief Products For Humans, HAI, Food Borne Illness!,------ Results From Pico skin Relief 100 People!

Pico-Physics products are positively charged atoms with trillions of millhouse energy from 5400 trillion atoms per square inch that can disassemble chemicals, soils, bacteria, fungi, virus and small insects and eliminate pestcides! Plus feed plants and solved the translocation problems of agriculture, not to mention we grow Skin or "Tissue Engineering" on humans.

Pico Skin Relief (Physical Chemisty) using Carbon Atoms only!

Home Pico Now
Not Future!
About Our History Future Skin
Products
FDA
EAFUS Drugs
Housewives 54%
Higher Cancer Rate
Press Release
SGS Skin Test E-Coli Candida
MSRA
Staphylococcus
Staph Strep E-coli
Salmonella
Pseudomonas
Gram-Positive
Bacteria
Geobacillus
Tests
Chlorine Equal Antibiotics
Dont Work

Composition
Human Body!
Dermotologist
Nightmare
Not Good
For Business
Skin
Lightening
Genetic Blistering 100 Testimonals Dog Ear Infections Lamb Gangrene Infection
Psoriasis Squamous Cancer Arm Dandruff Ringworms Diabetic Amputation Growing Human Skin
or Tissue Engineering
Whooping Cough
Pneumonia
Root Canals
Dentures
Parasite, Scabies Candida Yeast
Cradle Cape
Seborrheic Dermatitis
Cellulitis Head Lice Panama Man Amputation
Stopped
Poisons Ivy, Oak, Sumac


Pico Skin Relief is 4000 times smaller than Bacterium and 4 times smaller than DNA, and 6,666,666 times smaller than Ant.
Product in a Centrifuge at 25,000 and 100,000 RPM would not separate. Lab Manager said this really small stuff.
Product will create Skin which is nails, hair, tissue engineering and Skin regeneration.

Atoms alone or in covalent bond can create even a more powerful electromechanical reaction than a chemical reaction. They can disasemble organic material one atom per atom at a time. From a single layer of this picotechnology size atoms you could easily have 1700 to 10,000 trillion particles per square inch per layer of material! They can than work on the fungi, bacteria, or virues to eliminate them in less than 4 days just like reported in the Readers Digest in 1929. Recently reported to us that after 3 days Shingles, Basil Cell Cancer, Squamous Cell Cancer, Poisin Ivy, Oak, Sumac, Diabetic Ulcers, Wounds, Plaque Psoriais, Genetic Blistering, Head lice, Whopping Cough and Skin grown on humans, The medical experts at Riken in Japan say growing Skin on humans is 10 years away, Rubbish we have done tissue engineering for 10 years! And so much more benefits to list. This product grows skin and prevents amputations and its free.


The daughter of Chinese refugees, Chan Zuckenberg co-owner of Facebook is a big believer in Traditional Chinese Medicine and holistic health regimes. She believes that western medicine is incomplete, only striving to treat illness, rather than get to its root cause and cure it. Chan and Zuckerberg hope to find cures for thousands of disease now plaguing our society. Pico-Technology can already can do hundreds and hundreds she might even call!

To the interdisciplinary physics fields, which define partially sciences of their own! We believe Pico-Physics is different as we use the atoms singularly! What we do to make a product is collect 1 to 3 atoms and bond them together or not for our purposes in Medical, Agriculture, Cleaning and Chemical use elimination! We have replaced for example Hydrochloric acid or Muriatic Acid, and Acetone with something you can drink. Welcome "BACK" to Electro-Mechanical Single Element Physics (We just call it Pico-Physics) vs "Patented" Organic Chemistry gone since 1930! We can deliver this product daily in a liquid form in truckloads of 9000 gallons per shift daily.

Astrophysics, the physics in the universe, including the properties and interactions of celestial bodies in astronomy.
Biophysics, studying the physical interactions of biological processes.
Chemical physics, the science of physical relations in chemistry.
Econophysics, dealing with physical processes and their relations in the science of economy.
Engineering physics, the combined discipline of physics and engineering.
Geophysics, the sciences of physical relations on our planet.
Mathematical physics, mathematics pertaining to physical problems.
Medical physics, the application of physics to prevention, diagnosis, and treatment.
Particle physics studies the nature of particles, while nuclear physics studies the atomic nuclei.
Physical chemistry, dealing with physical processes and their relations in the science of physical chemistry.
Quantum computing, the study of quantum-mechanical computation systems.
And many more forms of physics!


Pico Technology or PicoTechnology

Overview

1 Picometer is 1000 times smaller than Nanometer, We refer to this as Pico-Physics and we have made products for 20 years with and without of covalent bonds for over 4000 products for industrial applications in Medical, Agriculture, Cleaning and Chemical Elimination or replacement.

Applications

PicoTechnology is a term used by some futurists to refer to structuring of matter on a true picometer scale. Picotechnology was described as involving the alteration of the structure and chemical properties of individual atoms, typically through the manipulation of energy states of electrons within an atom to produce states with unusual properties, producing some form of exotic atom. Let me state this is not furtistic when you have done it for 20 years its about 200 years old if not a billion.

Alternatively, picotechnology is used by some researchers in nanotechnology to refer to the fabrication of structures where atoms and devices are positioned with sub-nanometer accuracy. This is important where interaction with a single atom or molecule is desired.

Products are 100% Single Atom Pico-Physics and 0% Chemistry, Its time to change!


Pico LLC been in business for 20 years using Picotechnology or single atoms not molecules or any form of Chemistry. No active ingredients or inerts, just electro mechanical action of the product. We have production and trails all over the world with great success such as Amity University-India Arizona State University Asia Medical and Agriculture Laboratory R&D center Auburn University Australian Bio-Security-Australia Botanical Gardens-Brunei Becks Seed Cornell University Delta College-India Eurofins Florida State Bio-Control Facility Genetic ID GMO Testing Hulst Research Farm Services Iowa State University Louisiana State University Maryland Agriculture Department Michigan State University Midwest Laboratories Mississippi State University Molecular Biology Group-Canada North Carolina A&T North Carolina State University Ohio State University Oregon State University Panama Organic Fertilizer Certicaton Panama Organic Pesticide Certication Pennsylvania State University Rajiv Gandhi University Republic of the Panama Republic of the Phillippines Rutgers University S&R Consulting SGS Laboratory Shanxi Agriculture University-China Soil Foodweb Institute South Dakota State University South Vietnam Foods-Vietnam State of Florida State of Mayland Syngenta-Greensboro Texas A&M University Thailand FDA Registration-Thailand Tien Giang Agricultural Center-Vietnam Tiengiang Food Company – Vietnam University of Florida University of Georgia University of Guelph-Canada University of Kentucky University of Madras-India University of Massachusetts University of Miami University of Nebraska Lincoln University of Tennessee Vietnam Government - MARD-Vietnam Wellab-Hong Kong, Ukraine, Kurdistan, South Africe, Zambia, New Zealand, Turkey, Nigeria, Canada, Columbia, Myanmar, and so many more!



Albert Einstein Says!

Education is what remains after one has forgotten what one has learned in school!
The only thing that interferes with your learning is your education!
The only source of knowledge is your own experience!
I fear the day technology will surpasses our ability human understanding. The world will have a generation of idiots!
Change the way people think and people will never be the same!
It is difficult to get a man to understand something when his salary depends upon his not understanding it, Upton Sinclair.


Talk is cheap and the words nanotechnology and picotechnology are missed used for beware products are not even picotechnology. So we have the proof below from University of Miami, Florida and in Restch-Technology China that validated our claim of size at 600 picometers. There is no such thing as an atom of 600 picometers, because our product is made of a single atoms of 340 pm its simple a covalent bond of 2 atoms.

University of Miami
Scanning Electronic Material (SEM) Lab
Manager Sue Decker

Subject: Sub Nanotechnology - Picotechnology

Date: 2-10-2007

Hi Don Wilshe

I Anaylzed your product with the SEM this week of your solution. I used it at 1:1, 1:100 with water and lastly straight out of the jug 100%. In both the 1:1 and 1:100 there are droplets with a small grains in the size of 2-4 nanometers. (Very Small). The droplets in the 100% straight solution have similar size particles around the edges, but inside the grain is less than 1 nanometer. I don't know if this is of any help to you but let me know if you need anything else. The University of Miami Center for Advanced Microscopy (UMCAM) provides SEM (scanning electron microscopy).

Sue Decker

Restch-Technology China validated the size at 600 picometers.





,

We believe Pico-Physics is unique as we use the atoms singularly, no molecules! What we do to make a
product is collect 1 to 3 atoms from the periodic table and bond them together or not for our purposes
in Medical, Agriculture, Cleaning and Chemical use elimination! This is not rocket science its Common
Sense and or pure thought!


--

We know Picotechnology is now not later as we have done it for 20 years and well aware of the benefits. 3 working papers on picotechnology and their conclusion the same its futuristic!

Looking forward picotechnology, No Its here now!

Nanotechnology and picotechnology to increase tissue growth

Conclusion 1 from 1st paper

There is extremely little research on Picotechnology it seems although we have been doing it 20 years. I was able to find these conclusiions that might support each other! Lastly, this paper will emphasize a new field, picotechnology, in which researchers are altering electron distributions around atoms to promote surface energy to achieve similar increased tissue growth, decreased inflammation, and inhibited infection without potential nanomaterial toxicity concerns. A potentially less toxic method that is used to increase tissue growth and create the next generation of tissue engineering materials is to use Picotechnology. Picotechnology is a new term used to describe the control of electron distribution around atoms, so as to provide desirable properties. Having control over electron distribution may greatly change surface energy and, thus, the way that proteins adsorb onto a material. Therefore, through the excitement or rearrangement of electrons around atoms, one has the ability to influence many cellular functions including cell movement, intracellular transport to organelles, adhesion, growth, and ECM formation. The promise of picotechnology.

Despite the promise of picotechnology, relatively little research has been conducted in this field. The control of cellular microtubules (MTs) through picotechnology is extremely interesting to consider. MTs s are cylindrical cellular formations 25 nm in diameter, and they are made out of tubulins. Dynamic instability due to MT plus end-binding proteins, also called “plus end-tracking proteins”, are able to “surf” the dynamic ends of MTs. According to recent reports, when tips are expressed as green fluorescent proteins, the fluorescence is the brightest at the MT and decreases in intensity toward the minus end of the MT, forming a comet tail. It is envisioned that one could use external stimulation to excite the MT and end-binding proteins to promote the movement of cells using picotechnology. This may be a less toxic manner through which to alter surface energy to increase tissue growth since electron distributions can be changed for numerous macro-, micro-, or nanomaterials. Future strategies may also include the use of picotechnology instead of nanotechnology to reduce the toxicity since electrons can be excited in any macro-, micro-, or nanomaterials. The change in electron distribution, along with the associated charge redistribution, can alter surface energetics to change the adsorption of certain proteins (as well as cellular functions).

Emerging Trends of Nanotechnology towards Picotechnology Energy

Conclusion 2 from 2nd paper!

The concept of pico scale of measurement in physics, environment, biology and chemistry is highlighted with examples of metal ions, climatic conditions, and bioassemblies. The integrated monitoring using picoscope and monitoring oscilloscope for use in proteins linked with metals in supramolecular macromolecules is described with potentials of picomolar science. The temperature, humidity and electricity and their regulatory factors play a significant role in biomedical, automotive actions of biomolecules in the environment. The proteins and their regulatory metal cofactors play a significant role in structural-functional actions of biomolecules in the body. Picodevices have paved the way to determine minute amounts of metabolites, hormones, nucleotides. Picochips and pico-inspired biological applications remain further attraction in future. Overall picotechnology remains to see as most powerful computation device in data simulation in physical, biological, engineering and environmental applications

This Riken Skin Growing Could Revolutionize Grafting.



A diagram of Skin, showing hair follicles, sweat pores and other parts of the organ.

Last year, in a lab in Japan, a mouse grew hair.

That may not sound like much of an accomplishment for a mouse, but it was an extraordinary feat for the scientists watching it. For the first time, Skin grown in a lab and then transplanted onto a mouse was doing all the things Skin is needed to do — produce sweat, secrete protective oils, grow hair.

In a study published in the journal Science Advances scientists from Japan’s RIKEN Center for Developmental Biology detail how they were able to craft fully functional Skin from stem cells made from the gums of mice. When transplanted onto mice with suppressed immune systems, the Skin integrated well and even made connections with surrounding nerve and muscle tissue.

Though they’re a good five to 10 years away from replicating the same technique in humans, the scientists say it has the potential to revolutionize Skin grafts, which currently rely on Skin taken from other parts of the body or still-flawed artificial Skin. The former poses medical challenges, and the latter lacks the ability to grow hair or produce oils like normal Skin — which, at best, makes the grafts look different from the rest of the body, and at worst can be a health hazard.

We are coming ever closer to the dream of being able to recreate actual organs in the lab for transplantation,” lead author Takashi Tsuji said in a We are coming ever closer to the dream

The project took advantage of a technique discovered in 2006 that allows researchers to genetically reprogram any old cell and turn it into a stem cell (technically known as an “ induced pluripotent stem cell This meant that cells taken from the mice’s gums could then be guided down a different developmental pathway using a chemical signal. When transplanted onto other mice, the Skin developed normally to form the various layers of Skin responsible for the organ’s diverse functions.

That’s vital, because Skin is more than just the packaging that keeps our innards from hanging out all over the place. The body’s largest organ is a thermostat, a producer of vitamins and lubricant, an energy warehouse and a bulwark against infection, not to mention one of our best sources of information about the world around us.

Many of those functions are eliminated in the current Skin transplant process. The grafted Skin can’t regulate temperature as well, since it doesn’t have the ability to produce sweat (which cools the body as it dries). Grafted Skin also lacks sebaceous glands — many patients have to oil their Skin constantly to keep it from drying out. And if the grafted Skin doesn’t link up with muscle and nerve cells, one of our most sensitive sensory organs is rendered inert.

The researchers didn’t test whether the Skin would work in mice without suppressed immune systems, and New York University dermatology chair Seth Orlow noted to U.S. News and World Report that the process the Japanese researchers used to develop the cells may be too “laborious” to be feasible for significant human transplants.

But John McGrath, a professor of molecular dermatology at King’s College London, told the BBC that researchers in his field had been waiting for this kind of study.

“It’s recapitulating normal Skin architecture,” he said. “So rather than having isolated bits of Skin [that don’t serve every function] … here we’ve actually got a whole box of stuff.”

If it works for humans, lab-grown Skin developed by Tsuji and his colleagues has the potential to help burn victims and people who suffer from some forms of hair loss and other medical conditions, Orlow told U.S. News and World Report

Beyond that, he added, “research like this is important because it is one step in a long journey of steps to eventual extraordinary therapies that lie ahead.”

Transitioning from Nanomedicine to Picomedicine
What’s on the Horizon ? Thomas J. Webster
Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA

Statement of Purpose: Inspired from biological systems, nanotechnology has already revolutionized medicine including improving the prevention, diagnosis, and treatment of numerous diseases. This talk will summarize efforts over the past decade that have synthesized novel nanoparticles, nanotubes, and other nanomaterials to improve medicine. Efforts focused on the use of nanomaterials to minimize immune cell interactions, inhibit infection, and increase tissue growth will be especially emphasized. Tissue systems covered will include the nervous system, orthopedics, bladder, cardiovascular, vascular, and the bladder. Due to complications translating in vitro to in vivo results, only in vivo studies will be emphasized here. Materials to be covered will include ceramics, metals, polymers, and composites thereof. Self-assembled nano-chemistries will also be emphasized. However, while significant promise has been made in using nanomaterials in medicine, particularly regenerative medicine, some problems remain (such as toxicity and manufacturing). This talk will further provide the latest concerning nanoparticle toxicity and manufacturing issues. Moreover, this talk will also introduce a new research direction in picotechnology which may generate materials even better for medicine that what nanotechnology has accomplished.

Methods: For orthopedic applications, numerous 3D tissue engineering scaffolds have been fabricated using polymers, ceramics, and metals. Osteoblast (bone forming cells) functions including adhesion (up to 4 h), proliferation (up to 5 days) and differentiation (up to 21 days) on different 3D tissue engineering scaffold topographies were systematically investigated [1]. Moreover, using a standard rat-calvarial defect model, 3D tissue engineering scaffolds were implanted and topographical effects on bone formation assessed. Similar studies have been conducted for cartilage applications using chondrocytes (cartilage producing cells) and rabbit osteochondral in vivo assays.

For anti-cancer implications, nanopatterned poly(lactic-co-glycolic acid) (PLGA, 50:50 PLG/PGA, wt%) 3D surfaces with similar surface chemistry but different topographies have been fabricated. Nanopatterned PLGA substrates were investigated for their ability to inhibit numerous cancer cell functions, including osteosarcoma, breast epithelial adenocarcinoma cell (MCF-7), and lung epithelial cancer cell adhesion, proliferation, apoptosis and vascular endothelial growth factor (VEGF) secretion using standard techniques [2].

For cardiovascular applications, 3D PLGA:carbon nanofiber (CNF) composites were formulated as a novel type of cardio-patch to promote cardiomyocyte (heart muscle) growth [3]. In this study, PLGA and CNF weight ratio densities were altered to investigate changes in cardiomyocyte functions including adhesion (up to 4 h), proliferation (up to 5 days), and protein (fibronectin and vitronectin) adsorption.

Results: For all materials, traditional methods such as scanning electron microscopy (SEM), Raman spectroscopy, and water contact angle measurements verified similar scaffold surface chemistry and wettability but varied topographies. Cytocompatibility in vitro and in vivo assays demonstrated enhanced osteoblast functions (including adhesion, proliferation, intracellular protein synthesis, alkaline phosphatase activity and extracellular calcium deposition) on nanostructured compared to nano-smooth 3D tissue engineering constructs. An SEM study of osteoblast attachment helped to explain the topographical impact substrates have on osteoblast functions by showing altered ?lopodia extensions and migration rates. Similar results have been observed for cartilage. In a novel manner, efforts have been made develop in situ sensors which can provide real time information on tissue growth.

Nanopatterned PLGA samples for cancer applications demonstrated for the first time significantly decreased cancer cell functions (including decreased proliferation rate, increased apoptosis and decreased VEGF synthesis) on 23 nm featured PLGA surfaces compared to all other PLGA surface topographies fabricated (specifically, nanosmooth and submicron rough 300 and 400 nm surface-featured PLGA surfaces) without the use of chemotherapeutics. In contrast, healthy cells proliferated more on the 23 nm featured PLGA surfaces compared to all other PLGA samples.

For cardiovascular applications, in vitro analysis indicated greater surface area and nanoroughness when increasing CNF ratio amounts until they reached a 25:75 [PLGA:CNF (wt:wt)] ratio where the surface roughness at the nanoscale decreased. Vitronectin and fibronectin adsorption assays showed greater initial adsorption on 3D scaffolds with greater nanoscale roughness which may provide a mechanism for greater cell responses on such nanostructured scaffolds.

In a move towards picotechnology, we have stimulated atoms in nanomaterials to control electron distributions to further increase surface energy. We have seen that through such control at the pico-level, we can achieve the best tissue growth.

Conclusions: Nanostructured polymers, metals, and ceramics promote bone, cartilage, anti-cancer (bone, breast, and lung), and cardiovascular applications. Recent studies controlling electron distributions at the picolevel have further promoted tissue growth.

This what what Pico 1 can do and have done it 20 years. We prevent amputations and eliminated Gangrene in 4 days before treatment! Whats missing from nanotechnology paper after paper is energy that picotechnology gives you. We have it "Energy" and see the Skin below since 2004 for Skin and wounds.







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Pico Technology LCC
Donald Wilshe
805 Cottage Hill Way
Brandon, Fl 33511
Email: donwilshe@biobased.us
Phone USA 800 995-9203 Direct to Cell.
Phone USA INTL 336-306-0193
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